A noun + をもとにして can be used to express "based on [noun]." The して portion is optional here. If the phrase is being used to describe another noun (for example, "a book based on my childhood"), then した is used instead.
日本のマンガをもとにしてたくさんのアニメやゲームが作られている。
There are lots of anime and games made that are based on Japanese manga.
去年リーさんは中国の留学生の時をもとに論文を書いたんだ。
Last year, Lee-san wrote an essay based on his time as a foreign exchange student in China.
これは、私の子供の時の経験をもとにした小説です。
This is a novel based on my experiences when I was a child.
母に買った映画は実際にあった話をもとにしたそうだな。
I hear that the movie I bought for my mom was based on a true story.
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